個人簡介

陳義傑，中共黨員，湖北省傑出青年基金獲得者，兼任湖北省食品科學技術學會副秘書長、湖北省衛生監督協會常務理事、湖北省首批中小微企業“科技副總”、湖北省科技特派員。主要研究方向為食品蛋白質化學與工程和食品合成生物學，主要圍繞食品蛋白/肽的物性和生物活性進行應用基礎研究，并以此進行新型功能蛋白/肽的合成與開發。近年來主持3項國家自然科學基金、國家科技支撐計劃子課題、湖北省傑出青年科學基金、教育部新教師基金，以及企業橫向課題等項目。參與湖北省技術創新計劃重大科技專項、湖北省自然科學基金創新群體等項目。參編《營養與代謝》教材，累計以第一/通訊作者在Food Hydrocolloids、Food Research International、Journal of Agricultural and Food Chemistry等食品領域TOP期刊雜志發表SCI科研論文20餘篇，轉讓專利1項。獲湖北省科技進步一等獎、教育部自然科學二等獎。

教育經曆

2007/09-2012/08 武漢大學生化與分子生物學系，博士
2003/06-2007/08 77779193永利官网生物工程，學士

工作經曆

2023-至今 77779193永利官网食77779193永利官网教授
2016-2023，77779193永利官网，食品化學與分子生物學系，副教授
2012-2016 77779193永利官网，食品化學與分子生物學系，講師

研究領域

研究領域：
1.食品蛋白質化學與工程——通過生物與食品學科交叉，從蛋白數量、分子結構等多維度系統深入研究食品蛋白質物性的形成機制，以及其生物活性的分子機制。基于機制的理解，對食品蛋白/肽進行設計與改造，指導新型功能蛋白/肽的開發。
2.食品合成生物學——利用分子克隆、酶工程、底盤細胞分子改造等方法進行功能蛋白的高效生物合成與制備。
3.食品分子營養——通過蛋白質組、轉錄組、分子計算模拟等方法，深入研究功能因子的活性機制和食品滋味形成機制。

科研項目

科研項目：
1.國家重點研發計劃項目子課題，低緻敏性兒童營養健康食品功效評價模式及産品标準構建，2023/12-2027/12，主持。
2.國家自然科學基金，冰核蛋白中不同結構域對成冰核活性的影響及機制研究，2020/01-2023/12，主持。
3.國家自然科學基金，豌豆分離蛋白穩定乳液的油/水界面蛋白定量研究，2018/01-2021/12，主持。
4.國家自然科學青年基金，茶樹菇Agrocybe aegerita中活性蛋白/肽的系統鑒定和功能研究，2014/01-2016/12，主持。
5.高等學校博士學科點專項科研基金，食用真菌茶樹菇活性蛋白AAL抗腫瘤機理，2014/01-2016/12，主持。
6.湖北省自然科學基金，茶樹菇子實體蛋白酶解制備活性肽的工藝及活性研究，2013/01-2015/12，主持。

成果獎勵

代表論文：
1.Sun, M.; Liu, D.; Yin, G.; Li, W.; Zhou, Y.; Lu, W.; Chen, Y.; Zhang, H.; Wei, F., Magnesium Ion Responses of Zwitterionic Phosphatidylethanolamine Head and Tail Groups Elucidated by Frequency-Resolved SFG-VS. The journal of physical chemistry letters 2023, 14, 2433-2440.
2.Song, R.; Jiang, C.; Zhu, J.; Liu, J.; Zhang, L.; Zuo, J.; Zheng, W.; Liu, S.; Huang, Q.; Wei, X.; Chen, Y., Expression of Ice Nucleation Protein in Bacillus amyloliquefaciens and Its Application in Food Freezing Process. Foods 2023, 12, 3896.
3.Han, F.; Shen, Q.; Zheng, W.; Zuo, J.; Zhu, X.; Li, J.; Peng, C.; Li, B.; Chen, Y., The Conformational Changes of Bovine Serum Albumin at the Air/Water Interface: HDX-MS and Interfacial Rheology Analysis. Foods 2023, 12, 1601.
4.Shen, Q.; Zheng, W.; Han, F.; Zuo, J.; Dai, J.; Tang, C.; Song, R.; Li, B.; Chen, Y., Air-water interfacial properties and quantitative description of pea protein isolate-Tween 20. Food Hydrocolloids 2023, 108568.
5.Shen, Q.; Dai, H.; Wen, L.; Zheng, W.; Li, B.; Dai, J.; Li, B.; Chen, Y., Effects of pH-shifting treatments on the emulsifying properties of rice protein isolates: Quantitative analysis of interfacial protein layer. Food Research International 2023, 164, 112306.
6.Shen, Q.; Li, J.; Shen, X.; Zhu, X.; Dai, J.; Tang, C.; Song, R.; Li, B.; Chen, Y., Linear and nonlinear interface rheological behaviors and structural properties of pea protein (vicilin, legumin, albumin). Food Hydrocolloids 2023, 139, 108500.
7.Shen, Q.; Luo, Y.; Zheng, W.; Xiong, T.; Han, F.; Zuo, J.; Dai, J.; Li, B.; Chen, Y., Nonlinear rheological behavior and quantitative proteomic analysis of pea protein isolates at the air-water interface. Food Hydrocolloids 2023, 135, 108115.
8.Shen, Q.; Zheng, W.; Han, F.; Dai, J.; Song, R.; Li, J.; Li, Y.; Li, B.; Chen, Y., Quantitative analysis and interfacial properties of mixed pea protein isolate-phospholipid adsorption layer. International journal of biological macromolecules 2023, 232, 123487.
9.Shen, Q.; Xiong, T.; Dai, J.; Chen, X.; Wang, L.; Li, Y.; Li, J.; Li, B.; Chen, Y., Effects of pH-shifting treatments on oil-water interfacial properties of pea protein isolates: Identification and quantification of proteins at interfacial protein layer. Food Hydrocolloids 2022, 133, 107937.
10.Shen, Q.; Xiong, T.; Zheng, W.; Luo, Y.; Peng, W.; Dai, J.; Song, R.; Li, Y.; Liu, S.; Li, B.; Chen, Y., The effects of thermal treatment on emulsifying properties of soy protein isolates: Interfacial rheology and quantitative proteomic analysis. Food Research International 2022, 157, 111326.
11.Zhan, F.; Tang, X.; Sobhy, R.; Li, B.; Chen, Y., Structural and rheology properties of pea protein isolate-stabilised emulsion gel: Effect of crosslinking with transglutaminase. International Journal of Food Science & Technology 2022, 57, 974-982.
12.Luo, Y.; Zheng, W.; Shen, Q.; Zhang, L.; Tang, C.; Song, R.; Liu, S.; Li, B.; Chen, Y., Adsorption kinetics and dilatational rheological properties of recombinant Pea Albumin-2 at the oil-water interface. Food Hydrocolloids 2021, 120, 106866.
13.Li, Y.; Li, Y.; Xia, J.; Yang, Q.; Chen, Y.; Sun, H., 3’-Sulfo-TF Antigen Determined by GAL3ST2/ST3GAL1 Is Essential for Antitumor Activity of Fungal Galectin AAL/AAGL. ACS Omega 2021, 6, 17379-17390.
14.Song, R.; Liang, T.; Shen, Q.; Liu, J.; Chen, Y., The optimization of production and characterization of antioxidant peptides from protein hydrolysates of Agrocybe aegerita. LWT- Food Science and Technology 2020, 134, 109987.
15.Zhan, F.; Ding, S.; Xie, W.; Zhu, X.; Hu, J.; Gao, J.; Li, B.; Chen, Y., Towards understanding the interaction of β-lactoglobulin with capsaicin: Multi-spectroscopic, thermodynamic, molecular docking and molecular dynamics simulation approaches. Food Hydrocolloids 2020, 105, 105767.
16.Zhan, F.; Shi, M.; Wang, Y.; Li, B.; Chen, Y., Effect of freeze-drying on interaction and functional properties of pea protein isolate/soy soluble polysaccharides complexes. Journal of Molecular Liquids 2019, 285, 658-667.
17.Xiong, T.; Ye, X. D.; Su, Y. T.; Chen, X.; Sun, H.; Li, B.; Chen, Y. J., Identification and quantification of proteins at adsorption layer of emulsion stabilized by pea protein isolates. Colloids and Surfaces B: Biointerfaces 2018, 171, 1-9.
18.Xiong, T.; Xiong, W.; Ge, M.; Xia, J.; Li, B.; Chen, Y., Effect of high intensity ultrasound on structure and foaming properties of pea protein isolate. Food Research International 2018, 109, 260-267.
19.Wang, Y.; Xu, S.; Xiong, W.; Pei, Y.; Li, B.; Chen, Y., Nanogels fabricated from bovine serum albumin and chitosan via self-assembly for delivery of anticancer drug. Colloids and surfaces. B, Biointerfaces 2016, 146, 107-13.
20.Huang, Q.; Ge, H.; Jin, W.; Shah, B. R.; Ye, S.; Hu, Y.; Li, B.; Chen, Y., Significant improvement for the functional properties of konjac glucomannan based on phase separation. International Journal of Food Science & Technology 2016, 51, 2396-2405.
21.Lin, L.; Xu, W.; Liang, H.; He, L.; Liu, S.; Li, Y.; Li, B.; Chen, Y., Construction of pH-sensitive lysozyme/pectin nanogel for tumor methotrexate delivery. Colloids and surfaces. B, Biointerfaces 2015, 126, 459-66.
22.Wang, Y.; Zheng, H.; Li, Y.; Li, B.; Chen, Y., One step procedure for desalting salty egg white and preparing fat analogue and its application in mayonnaise. Food Hydrocolloids 2015, 45, 317-326.
23.Chen, Y.; Jiang, S.; Jin, Y.; Yin, Y.; Yu, G.; Lan, X.; Cui, M.; Liang, Y.; Wong, B. H.; Guo, L.; Sun, H., Purification and characterization of an antitumor protein with deoxyribonuclease activity from edible mushroom Agrocybe aegerita. Molecular nutrition & food research 2012, 56, 1729-38.
24.Sun, H.; Ye, T.; Wang, Y.; Wang, L.; Chen, Y.; Li, B., Antioxidant activities of chick embryo egg hydrolysates. Food Science & Nutrition 2014, 2, 58-64.
25.Jiang, S.; Chen, Y. J.; Wang, M.; Yin, Y. L.; Pan, Y. F.; Gu, B. L.; Yu, G. J.; Li, Y. M.; Wong, B. H. C.; Liang, Y.; Sun, H., A novel lectin from Agrocybe aegerita shows high binding selectivity for terminal N-acetylglucosamine. Biochemical Journal 2012, 443, 369-378.
26.Yu, G. J.; Wang, M.; Huang, J.; Yin, Y. L.; Chen, Y. J.; Jiang, S.; Jin, Y. X.; Lan, X. Q.; Wong, B. H. C.; Liang, Y.; Sun, H., Deep Insight into the Ganoderma lucidum by Comprehensive Analysis of Its Transcriptome. PLOS ONE 2012, 7.
27.Liang, Y.; Chen, Y.; Liu, H.; Luan, R.; Che, T.; Jiang, S.; Xie, D.; Sun, H., The tumor rejection effect of protein components from medicinal fungus. Biomedicine & Preventive Nutrition 2011, 1, 245-254.

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