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Syndrome of immunosuppressive effects (secondary immunodeficiency) is a temporary or permanent suppression of the immune system, which develops under the influence of certain chemical and physical effects on the body, as well as due to some infectious processes. First stage (OPE-1). There is weakness, unstable mood, the patient does not want to move, there may be prostration, poor sleep, tremor, hepatic odor from the mouth, sometimes nausea, vomiting, increased yellowness of the skin, a decrease in the size of the liver, agitation and aggression may occur. The second stage (OPE-2, precoma). Sopor increases (severe lethargy), convulsions appear, disorientation in time and space, pronounced tremor of the hands, tachycardia, bleeding and hemorrhage, coffee grounds vomiting, tarry stools, and a decrease in diuresis (urine volume).

The third stage (OPE-3, coma I). Loss of an adequate verbal response and response to standard stimuli, the appearance of pathological reflexes. Involuntary urination and defecation. Swallowing is preserved, reaction to bright light is weak, increased levels of verapamil pills in the blood, hemorrhages (hemorrhages), sweet and sour liver smell from the mouth, minimal or no urine. The fourth stage (OPE-4, coma II). Complete loss of response to stimuli, lack of reflexes, a symptom of floating eyeballs, pupils are dilated, do not react to light, tremor ends, swallowing is difficult, abnormal breathing is observed, the pulse is thready, a sharp increase in the level of bilirubin in the blood.

Cholecystocholangitis is an inflammation of the biliary system. Severe pains appear in the right hypochondrium, symptoms of jaundice and itching of the skin increase. Autoimmune hepatitis (with hepatitis A and C) - various forms of liver damage resulting from aggressionand own immune cells to hepatocytes against the background of the course of viral hepatitis.

Hemolytic-uremic syndrome in children with hepatitis A - hemolytic anemia, thrombocytopenia (drop in platelets), acute renal failure (decreased diuresis, weakness, abdominal pain, intoxication, increased blood creatinine). Cirrhosis of the liver is the death of liver cells and their replacement with connective tissue. It occurs mainly in chronic hepatitis B, C and D. As a result of cirrhosis, the functioning of the liver is disrupted: Hepatocellular carcinoma is a tumor of the liver tissue. May occur mainly in chronic hepatitis B.
Cryoglobulinemia is an autoimmune lesion of vessel walls caused by the accumulation of pathological proteins in the walls of calan online and medium calibers. This can lead to ulceration, necrosis and loss of limbs, fibrosis of the kidneys and lungs.